OVERVIEW
BACKGROUND
AND SIGNIFICANCE
Introduction
Confluence
of Biological Data and Computing Power
Broad Goal
Bottom-Up Approach
Scope
Significance
IMPACT
Improving
Access to Protein Structure Modeling and Docking
Biology in Three
Dimensions
Combining
Experiment and Computation
Large-Scale
Viewpoint: Across Networks and Genomes
Human Health
CHALLENGES
CENTER CORES
Core 1&2:
Genome-Wide Mapping of Protein Interactions
Core 3: Driving
Biological Projects
DBP 1: Development of Novel Antiparasitic
Chemotherapeutics
DBP 2: Protein-Protein Interactions: Macromolecular
Complexes and Networks
DBP 3: Functional and Computational Analysis
of SNPs in Drug Response Genes
Core 4: Service
to the Biomedical Community
Core 5: Training
Center's Graduate and Postgraduate Students, and the Broad Biomedical
Community
Core 6: Dissemination
of Tools, Data, and Discoveries
Core 7: Management
and Oversight
INVESTIGATORS
AND ENVIRONMENT
Origins of the
Center
Computing
Resources of the Center
Environment
of the Center
A CASE FOR LAUNCHING
THE CENTER
LITERATURE
CITED